Regulation of embryo survival in cattle.
نویسندگان
چکیده
Evidence is presented that bovine somatotrophin (bST) treatment of lactating dairy cows enhances both expression of oviductal insulin-like growth factor II (IGF-II) mRNA and endometrial insulin-like growth factor binding protein 3 (IGFBP-3) mRNA between day 3 and day 7 of the oestrous cycle. mRNA encoding growth hormone (GH) receptor in endometrial tissues increased between day 3 and day 7 of the oestrous cycle. The changes induced by bST treatment may contribute to stimulation of embryo development and increase pregnancy rates in lactating dairy cows. Additive effects of bST and rb interferon tau (rbIFN-tau) to inhibit phorbol ester induction of prostaglandin F2alpha secretion in immortalized bovine endometrial cells indicates that there is interplay between their signal transduction pathways. Non-lactating dairy cows were killed at day 17 after oestrus to evaluate the effects of pregnancy status (cyclic versus pregnant) and bST (bST versus control) treatment on endometrial gene expression. Distinctly different mRNA and protein responses were detected between cyclic and pregnant cows that were related to luteolytic-antiluteolytic drive (that is expression of progesterone receptor, oxytocin receptor, oestradiol receptor alpha and prostaglandin GH synthase 2 (PGHS-2)). The bST-induced changes in PGHS-2 protein (+), oxytocin receptor mRNA (+) and oestrogen receptor alpha protein (+) may potentially affect the mechanisms associated with maintenance of pregnancy. Two experiments were conducted to evaluate whether ovarian follicular suppression induced by biodegradable deslorelin implants would reduce either early or late embryo losses. A 450 microg deslorelin implant used to induce ovulation in a timed insemination programme decreased subsequent follicular development and tended to reduce early embryo losses, whereas a 2.1 mg deslorelin implant failed to reduce late embryonic losses when inserted on day 27 of pregnancy.
منابع مشابه
EFFBCT OF OIL ON EMBRYONIC DEVELOPMENT IN V%TRO AND ON EMBRYO SURVIVAL AFTER ONE-STEP VITRIFICATION IN CAttLE
متن کامل
In Vitro Development of Cattle Embryo as Affected By Glucose, Serum and EDTA
Purpose: The aim of this study was to evaluate the effect of different modifications of sequential synthetic oviductal_fluid (SOF) culture system on developmental competence of in vitro matured/fertilized cattle embryos. Materials and Methods: Bovine oocytes were matured and fertilized in vitro and then presumptive zygotes were randomly cultured for up to 9 days in different modifications of SO...
متن کاملEmbryo Transferfortrans Cervicalin Cattle
The aim of this study was to analyze the incidence of stage of embryonic development, embryo quality and the time of transfer on pregnancy rate in embryo transfer program timed. We were worked a total of 23Holsteincowsasembryo donors, super-ovulated with gonadotropin of pregnant mare serum (PMSG) (2500 3000UI).69 cows were used as recipients of Holstein dairy heifers with an age of20 months and...
متن کاملGenetic and Economic Aspects of Applying Embryo Transfer in Traditional and Genomic Evaluation in Iranian Holstein Dairy Cattle
Embryo transfer (ET) in Holstein dairy cattle became an important commercial enterprise after the introduction of non-surgical recovery technique. Embryo transfer could increase the reproductive rate of genetically superior cows. The objectives of the present study were to evaluate the use of ET in Iranian Holstein dairy cattle to increase selection intensity on the dam side, economically; esti...
متن کاملEmbryo Transferfortrans Cervicalin Cattle
The aim of this study was to analyze the incidence of stage of embryonic development, embryo quality and the time of transfer on pregnancy rate in embryo transfer program timed. We were worked a total of 23Holsteincowsasembryo donors, super-ovulated with gonadotropin of pregnant mare serum (PMSG) (2500 3000UI).69 cows were used as recipients of Holstein dairy heifers with an age of20 months and...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Reproduction (Cambridge, England) Supplement
دوره 61 شماره
صفحات -
تاریخ انتشار 2003